VHL: A rare and cyclical condition1–3

Explore cyst and tumor manifestations
associated with VHL disease.

VHL disease is a rare condition that can cause recurrent cyst and tumor growth over the course of a patient’s lifetime.1–4

VHL disease is a largely heritable
condition, with

Brain and Spinal Cord

  • Central nervous system (CNS) hemangioblastomas are the most common tumors in patients with VHL disease, affecting up to 80% of patients with VHL disease.4
  • The average age of presentation is 33 years.4
Possible symptoms
  • Depending on where they appear, hemangioblastomas may cause
    headaches, vomiting, ataxia and gait
    disturbances, pain, sensory and motor loss,
    or severe defects including vision loss.2,4,5
Learn more about key clinical
characteristics of VHL disease
with Dr. Brian M. Shuch.

VHL = Von Hippel-Lindau.